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  • Title: Rosette formation by human T and B lymphocytes in the presence of adrenergic and cholinergic drugs.
    Author: Ferreira GG, Brascher HK, Javierre MQ, Sassine WA, Lima AO.
    Journal: Experientia; 1976 Dec 15; 32(12):1594-6. PubMed ID: 191281.
    Abstract:
    It was shown that adrenergic drugs, which increase the intracellular levels of cAMP, inhibit the rosette formation by T-lymphocytes, but stimulate the rosettes produced by B-lymphocytes. Cholinergic drugs, which increase the levels of cGMP, on the contrary, stimulate the formation of rosettes by T-lymphocytes but inhibit those produced by B-lymphocytes.
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