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  • Title: Soluble fibers inhibit carotenoid micellization in vitro and uptake by Caco-2 cells.
    Author: Yonekura L, Nagao A.
    Journal: Biosci Biotechnol Biochem; 2009 Jan; 73(1):196-9. PubMed ID: 19129646.
    Abstract:
    We evaluated the effects of soluble fibers on beta-carotene and lutein micellization during simulated digestion in vitro, and on carotenoid uptake from mixed micelles by Caco-2 cells. Medium- and high-viscosity alginates and pectins inhibited carotenoid micellization and cellular uptake relative to the fiber-free control. Alginates, carboxy-methylcelluloses, and methylcelluloses inhibited beta-carotene uptake mainly by increasing medium viscosity, but pectins might inhibit carotenoid uptake by additional mechanisms.
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