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  • Title: Antimicrobial activity of commercial Olea europaea (olive) leaf extract.
    Author: Sudjana AN, D'Orazio C, Ryan V, Rasool N, Ng J, Islam N, Riley TV, Hammer KA.
    Journal: Int J Antimicrob Agents; 2009 May; 33(5):461-3. PubMed ID: 19135874.
    Abstract:
    The aim of this research was to investigate the activity of a commercial extract derived from the leaves of Olea europaea (olive) against a wide range of microorganisms (n=122). Using agar dilution and broth microdilution techniques, olive leaf extract was found to be most active against Campylobacter jejuni, Helicobacter pylori and Staphylococcus aureus [including meticillin-resistant S. aureus (MRSA)], with minimum inhibitory concentrations (MICs) as low as 0.31-0.78% (v/v). In contrast, the extract showed little activity against all other test organisms (n=79), with MICs for most ranging from 6.25% to 50% (v/v). In conclusion, olive leaf extract was not broad-spectrum in action, showing appreciable activity only against H. pylori, C. jejuni, S. aureus and MRSA. Given this specific activity, olive leaf extract may have a role in regulating the composition of the gastric flora by selectively reducing levels of H. pylori and C. jejuni.
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