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  • Title: Dedifferentiated liposarcoma of the retroperitoneum with osteosarcomatous component: report of two cases.
    Author: Toshiyasu T, Ehara S, Yamaguchi T, Nishida J, Shiraishi H.
    Journal: Clin Imaging; 2009; 33(1):70-4. PubMed ID: 19135935.
    Abstract:
    We describe two cases of ossified soft tissue tumors of the retroperitoneum. Computed tomographic and magnetic resonance imaging both revealed retroperitoneal masses consisting of two components -- densely ossified and lipid-rich components. In one case, a 50-year-old man, a histological diagnosis of dedifferentiated liposarcoma with osteosarcoma was made based on the needle biopsy of the two components. In another case, a 54-year-old man, surgical resection of the complex perirenal mass was performed and the same diagnosis was made. Although an ossified component represent high-grade lesion, the fatty component is an important clue to the diagnosis of dedifferentiated liposarcoma. The imaging features may be similar to those of malignant mesenchymoma, which is not a currently used term.
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