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  • Title: Concurrent smoking-related interstitial lung diseases in a single patient.
    Author: Altayeh A, Alkhankan F, Triest W, Badin S.
    Journal: South Med J; 2009 Feb; 102(2):180-3. PubMed ID: 19139702.
    Abstract:
    The three smoking-related interstitial lung diseases (ILD) include desquamative interstitial pneumonia (DIP), respiratory bronchiolitis-associated interstitial lung disease (RB-ILD), and pulmonary Langerhans cell histiocytosis (PLCH). They are considered discrete entities, yet it is not unusual to find a mixture of pathologic features rendering the histopathologic diagnosis difficult. It is uncommon to have overlap in the different radiologic findings between these diseases. We present a unique case, in that the extent of DIP and PLCH-like changes were manifested both histologically and on high resolution computed tomography (HRCT) with ground-glass attenuation and upper lobe cystic changes suggestive of both diseases.
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