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  • Title: Ménière's disease is a viral neuropathy.
    Author: Gacek RR.
    Journal: ORL J Otorhinolaryngol Relat Spec; 2009; 71(2):78-86. PubMed ID: 19142031.
    Abstract:
    Morphological and clinical evidence supports a viral neuropathy in Ménière's disease (MD). Quantitative examination of 11 sectioned temporal bones (TBs) from 8 patients with a history of MD revealed a significant loss of vestibular ganglion cells in both the endolymph hydropic (EH) and non-EH ears. Transmission electron microscopy of vestibular ganglion cells excised from a patient with MD revealed viral particles enclosed in transport vesicles. Antiviral treatment controlled vertigo in 73 of 86 patients with vestibular neuronitis (85%) and 32 of 35 patients with MD (91%).
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