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  • Title: Successful pregnancy after treatment for ovarian malignant teratoma with growing teratoma syndrome.
    Author: Tzortzatos G, Sioutas A, Schedvins K.
    Journal: Fertil Steril; 2009 Mar; 91(3):936.e1-3. PubMed ID: 19152879.
    Abstract:
    OBJECTIVE: To report a case of successful IVF-pregnancy after treatment for ovarian growing teratoma syndrome. DESIGN: Case report. SETTING: Gynecologic department at a university hospital. PATIENT(S): A 20-year-old woman, gravida 0 para 0, was diagnosed with malignant teratoma of the ovary. She was treated by unilateral salpingo-oophorectomy and chemotherapy. A couple of years later she was diagnosed with growing teratoma syndrome. INTERVENTION(S): Fertility-preserving surgery with unilateral salpingo-oophorectomy and chemotherapy. In vitro fertilization. MAIN OUTCOME MEASURE(S): Disease free, successful pregnancy. RESULT(S): After treatment for ovarian immature teratoma and growing teratoma syndrome the patient was free of the disease. She underwent in vitro fertilization treatment with autologous embryo transfer and gave birth to a healthy child. CONCLUSION(S): Growing teratoma syndrome is an extremely rare metastatic complication of a malignant germ cell tumor after a combination treatment with surgery and adjuvant chemotherapy. This case shows that successful pregnancy outcome is possible after effective treatment for ovarian growing teratoma syndrome.
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