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  • Title: Lifetime substance abuse, family history of alcohol abuse/dependence and novelty seeking in eating disorders: comparison study of eating disorder subgroups.
    Author: Krug I, Pinheiro AP, Bulik C, Jiménez-Murcia S, Granero R, Penelo E, Masuet C, Agüera Z, Fernández-Aranda F.
    Journal: Psychiatry Clin Neurosci; 2009 Feb; 63(1):82-7. PubMed ID: 19154214.
    Abstract:
    AIM: To assess lifetime substance abuse, family history of alcohol abuse/dependence, and novelty seeking in three different eating disorder groups (anorexia nervosa-restrictive; anorexia nervosa-binge eating/purging; anorexia nervosa to bulimia nervosa). METHOD: A total sample of 371 eating disorder patients participated in the current study. Assessment measures included the prevalence of substance abuse and family history of alcohol abuse/dependence as well as the novelty-seeking subscale of the Temperament and Character Inventory-Revised. RESULTS: Significant differences across groups were detected for lifetime substance abuse, with anorexia nervosa-restrictive individuals exhibiting a significant lower prevalence than the anorexia nervosa to bulimia nervosa and anorexia nervosa-binge eating/ purging patients (P < 0.01). For family history of alcohol abuse/dependence the same pattern was observed (P = 0.04). Novelty seeking was associated with substance abuse (P = 0.002), with the anorexia nervosa to bulimia nervosa group exhibiting significantly higher scores on the novelty-seeking scale than the other two groups (P < 0.001). But family history of alcohol abuse/dependence was not related to novelty seeking (P = 0.092). CONCLUSION: Lifetime substance abuse appears to be more prevalent in anorexia nervosa patients with bulimic features. Higher novelty-seeking scores may be associated with diagnosis cross-over.
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