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Title: The distinct roles of JAM-A in reovirus pathogenesis. Author: Coyne CB. Journal: Cell Host Microbe; 2009 Jan 22; 5(1):3-5. PubMed ID: 19154981. Abstract: Despite their fundamental role in host defense, many components of epithelial and endothelial tight junctions serve as viral receptors. In this issue of Cell Host & Microbe, Antar et al. (2009) provide striking in vivo evidence that the broadly expressed reovirus receptor JAM-A plays a specific role in reovirus dissemination.[Abstract] [Full Text] [Related] [New Search]