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  • Title: [Recent developments in biopsy diagnosis of early and undefined liver tumors].
    Author: Longerich T, Schirmacher P.
    Journal: Z Gastroenterol; 2009 Jan; 47(1):30-6. PubMed ID: 19156590.
    Abstract:
    Biopsy diagnosis of early and highly differentiated liver tumors is difficult and complex. Modern pathology has met this challenge by several different means; elaborate morphological algorithms and novel immunohistological markers support the differential diagnosis of highly differentiated HCC and a new, predictive molecular pathological and histological classification of liver cell adenoma was developed. By these new diagnostic tools together with the so-called 'matrix diagnosis' a reliable diagnostic classification is now feasible in the vast majority of these difficult cases.
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