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  • Title: Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2006-2008).
    Author: Breadmore MC, Thabano JR, Dawod M, Kazarian AA, Quirino JP, Guijt RM.
    Journal: Electrophoresis; 2009 Jan; 30(1):230-48. PubMed ID: 19156661.
    Abstract:
    Poor sensitivity is still considered to be one of the major limitations of electrophoresis, which is surprising given the power, flexibility and versatility of many of the approaches to on-line concentration that have developed over the last 20 years. This is still a very active area of interest and this review will cover developments in the field over the last two years since the last review (Electrophoresis 2007, 28, 254-281) through to June 2008. It includes developments in the fields of stacking, covering all methods from field-amplified sample stacking and large volume sample stacking, through to ITP, dynamic pH junction and sweeping. Attention is also given to on-line or in-line extraction methods that have been used for electrophoresis.
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