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  • Title: [Physiopathologic aspects of microcirculation in intensive care].
    Author: Siegenthaler N, Giraud R, Romand JA, Bendjelid K.
    Journal: Rev Med Suisse; 2008 Dec 10; 4(183):2696-701. PubMed ID: 19157284.
    Abstract:
    In critical care patients, microvascular alterations and perfusion heterogeneity play an important role in the persistence of cellular hypoxia despite a satisfactory functioning of the macrocirculation. Advance in the knowledge of microcirculatory pathophysiology, and its relation with the macrocirculation could be in the future a way to improve the outcome of critically ill patients. Moreover, the evolution of clinical practice towards microcirculation monitoring as a standard of care, with new therapeutic targets aimed to increase tissue perfusion, could be a revolution in critical care practice.
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