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  • Title: Atypical carcinoid of the larynx and potential complications of the carcinoid syndrome: a case report.
    Author: Seshamani M, Einhorn E, Mirza N.
    Journal: Ear Nose Throat J; 2009 Jan; 88(1):E1. PubMed ID: 19172557.
    Abstract:
    A 47-year-old man with a history of allergic rhinitis presented with a several-month history of nasal symptoms and gastroesophageal reflux disease. He also had clinical depression, for which he had been taking a selective serotonin reuptake inhibitor (SSRI). During evaluation, flexible laryngoscopy incidentally detected a left interarytenoid polyp. Biopsy identified the lesion as a moderately differentiated neuroendocrine carcinoma. In addition to conducting a metastatic workup, we determined that it was necessary to evaluate the functional status of the tumor prior to excision because the SSRI could precipitate a carcinoid syndrome. We discuss the characteristics and management of different neuroendocrine carcinomas of the larynx, and we review the potential complications of the carcinoid syndrome.
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