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  • Title: Lipophilic 99mTc-nitride radiopharmaceuticals as potential myocardial imaging agents.
    Author: Dilworth JR, Archer CM, Latham IA, Kelly JD, Griffiths DV, York DC, Mahoney PM, Higley B.
    Journal: Int J Rad Appl Instrum B; 1991; 18(5):547-50. PubMed ID: 1917524.
    Abstract:
    Monocationic 99mTc-nitrido complexes of a variety of diphosphine ligands have been prepared and the in vivo distribution of such cations has been examined in Sprague-Dawley rats. These complexes show initially high myocardial uptake with subsequent wash-out in this animal model. The lack of myocardial retention can be attributed to the facile in vivo reduction of these cations.
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