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  • Title: Primary structures of cytotoxic factors isolated from habu (Trimeresurus flavoviridis) venom.
    Author: Yamakawa Y, Omori-Satoh T, Maeyama J.
    Journal: J Biochem; 1991 May; 109(5):667-9. PubMed ID: 1917887.
    Abstract:
    The amino acid sequence of a cytotoxic factor, CTF-I, isolated from the venom of the Japanese habu snake (Trimeresurus flavoviridis) has been determined through automatic phenylisothiocyanate degradation of the PE-protein and derived proteolytic peptides. CTF-I consists of 72 amino acids and contains an Arg-Gly-Asp sequence present in trigramin-like peptides isolated from other snake venoms. The primary structure of another cytotoxic factor, CTF-II, consisting of 75 amino acids, was deduced to comprise that of CTF-1 with an additional Glu-Leu-Leu-sequence at its N-terminal.
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