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Title: Extrahepatic portal hypertension due to familial protein S deficiency. Author: Shah I, Bhatnagar S. Journal: Indian Pediatr; 2009 Jan; 46(1):70-1. PubMed ID: 19179724. Abstract: Portal vein thrombosis (PVT) is a common cause of portal hypertension in children. A majority of children with PVT of unknown etiology have functional Protein C deficiency or abnormally elevated levels of anti-cardiolipin antibodies. We report an 8 years old Indian girl with portal cavernoma due to hereditary Protein S deficiency. We documented familial deficiency of Protein S in 2 asymptomatic siblings suggesting that this deficiency is the primary cause of portal vein thrombosis.[Abstract] [Full Text] [Related] [New Search]