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  • Title: Cytotoxic sorbicillinoids and bisorbicillinoids from a marine-derived fungus Trichoderma sp.
    Author: Du L, Zhu T, Li L, Cai S, Zhao B, Gu Q.
    Journal: Chem Pharm Bull (Tokyo); 2009 Feb; 57(2):220-3. PubMed ID: 19182418.
    Abstract:
    Four sorbicillinoids (1-4) and seven bisorbicillinoids (5-11), including two new compounds, 6-demethylsorbicillin (1) and 10,11-dihydrobisvertinolone (6), were isolated from a marine-derived fungus Trichoderma sp. Their cytotoxic activities against HL-60 cell line were evaluated by Sulforhodamine B (SRB) assay method and flow cytometric analysis.
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