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  • Title: Mitotic drivers--inhibitors of the Aurora B Kinase.
    Author: Keen N, Taylor S.
    Journal: Cancer Metastasis Rev; 2009 Jun; 28(1-2):185-95. PubMed ID: 19189202.
    Abstract:
    In this article we review the basis for current anti-mitotic, anti-cancer, therapy and the potential for Aurora B kinase inhibitors as a new differentiated class of agents--"mitotic drivers". We review the current understanding of Aurora B inhibition from basic cell biology to inhibitors currently undergoing clinical trials.
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