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  • Title: Ammocidins B, C and D, new cytotoxic 20-membered macrolides from Saccharothrix sp. AJ9571.
    Author: Murakami R, Shinozaki J, Kajiura T, Kozone I, Takagi M, Shin-Ya K, Seto H, Hayakawa Y.
    Journal: J Antibiot (Tokyo); 2009 Mar; 62(3):123-7. PubMed ID: 19198629.
    Abstract:
    Ammocidins B, C and D were isolated from the culture broth of Saccharothrix sp. AJ9571, an ammocidin A-producing strain. Their structures were determined by a detailed spectroscopic analysis and by a comparison of their NMR data with those of ammocidin A. Ammocidins A and B showed potent anti-proliferative activities against human cancer cell lines.
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