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  • Title: Anti-neutrophil cytoplasmic antibodies (ANCA): a seromarker for Wegener's granulomatosis.
    Author: Turner A.
    Journal: J Otolaryngol; 1991 Aug; 20(4):274-5. PubMed ID: 1920582.
    Abstract:
    Wegener's granulomatosis can be a difficult diagnosis to establish. It is not uncommon to require repeated biopsies over many months for histologic confirmation. A recently developed seromarker--anti-neutrophil cytoplasm antibody--ANCA (synonymous with anticytoplasmic autoantibody--ACPA) adds a new and valuable tool for diagnosis. The literature shows this to be a highly specific and sensitive test for Wegener's granulomatosis.
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