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  • Title: [An 8; 21 chromosome translocation associated leukemia presenting with large intestinal granulocytic sarcoma: a report of two cases].
    Author: Matsunaga T, Maseki N, Kaneko Y, Sampi K, Tsuchimochi T, Sakurai M, Hattori M.
    Journal: Rinsho Ketsueki; 1991 Jul; 32(7):782-5. PubMed ID: 1920842.
    Abstract:
    Two patients of acute myelogenous leukemia (AML) presented with a large intestinal tumor and related symptoms. They had a tumor in the rectum or the ascending colon. Bone marrow cells obtained from both patients showed a karyotype with t(8;21). Chromosomal findings in the former patient has already been reported in detail (Am J Hematol 4, 273, 1978). These findings and reports in the literature indicate that large intestinal tumor may not be rare in AML with an 8;21 translocation. Complete remission was achieved after chemotherapy, when their intestinal tumors disappeared.
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