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  • Title: [Immunomodulating therapy of a suppurative infection of the soft tissues].
    Author: Bobrova NV, Zemskov AM, Vysotskaia AT.
    Journal: Khirurgiia (Mosk); 1991 Jul; (7):28-32. PubMed ID: 1921193.
    Abstract:
    The initial immunological status in patients with purulent infection of the soft tissues is characterized by T-cell deficiency and relative hyperfunction of the B-immunity. The risk group with Grade 2-3T-cell immune deficiency takes up 44.5-77.5% and is encountered in patients with the B blood group and positive Rh factor in 79.1 +/- 5.2 and 70.8 +/- 4.3% of cases, respectively. Combination of sodium nucleinate and autohemotransfusion with the traditional therapy raises its efficacy. This is attended by correction of immunological disorders in T-cells and phagocytes, facilitates cleansing of the foci and increase of antibiotic sensitivity of the flora, and shortens the term of treatment.
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