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  • Title: Temsirolimus-induced glomerulopathy.
    Author: Izzedine H, Boostandoot E, Spano JP, Bardier A, Khayat D.
    Journal: Oncology; 2009; 76(3):170-2. PubMed ID: 19212144.
    Abstract:
    A 58-year-old man with advanced renal cell carcinoma developed grade 3 proteinuria (8.5 g/24 h) without microscopic hematuria or renal insufficiency five days after temsirolimus infusion. Kidney biopsy revealed ischemic glomeruli and focal segmental glomerulosclerosis lesion. Proteinuria level decreased to 2.80 g per day two weeks after temsirolimus withdrawal. Clinicians should be aware to this complication.
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