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  • Title: [Polycystic ovary syndrome with infertility].
    Author: Mourali M, Fkih C, Essoussi-Chikhaoui J, Ben Hadj HA, Binous N, Ben Zineb N.
    Journal: Tunis Med; 2008 Nov; 86(11):963-72. PubMed ID: 19213486.
    Abstract:
    BACKGROUND: The definition of the polycystic ovary syndrome has been controversial for a long time. Rotterdam consensus established precise criteria since two among three set the definition as follow: anovulation, hyperandrogenism and polycystic ovaries. The aim of this study is to stress on the particularity of ovarian dystrophy and the management of the resulting infertility that represents an important rate of medical counselling of women desiring pregnancy. METHODS: Literature review. RESULTS: Management consists in two parts: treating hyperinsulinism and stimulating ovulation. The "step up low dose" protocol is now taking the place of the classical "step down" protocol. Ovarian drilling have to be considered in case of resistance to Citrate of Clomifene. The hyperstimulation syndrome is the common complication to avoid by a regular following. The "coasting" represents an interesting alternative in case of an explosive response in order to obtain a controlled follicular failure. CONCLUSION: Clinical management of the PCOS have to be organized in regard to patient's age, history ,desire of pregnancy and medical staff experience.
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