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  • Title: A new cytotoxic homoisoflavonoid from Dracaena cambodiana.
    Author: Liu J, Mei WL, Wu J, Zhao YX, Peng M, Dai HF.
    Journal: J Asian Nat Prod Res; 2009; 11(2):192-5. PubMed ID: 19219735.
    Abstract:
    A new homoisoflavonoid, named cambodianol (1), together with the two known flavanes, (2S)-7,3'-dihydroxy-4'-methoxy-8-methylflavane (2) and (2R)-7,4'-dihydroxy-8-methylflavane (3), were isolated from the stems of Dracaena cambodiana. Their structures were determined based on HR-ESI-MS and spectroscopic techniques (UV, IR, 1D-, and 2D-NMR). Compound 1 exhibited significant cytotoxic activities against K562 and SGC-7901 with the IC(50) values of 1.4 and 2.9 microg/ml, respectively.
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