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Title: Diagnosis and management of osteoporosis. Author: Lash RW, Nicholson JM, Velez L, Van Harrison R, McCort J. Journal: Prim Care; 2009 Mar; 36(1):181-98, x. PubMed ID: 19231609. Abstract: Osteoporosis is a common disorder with significant morbidity and mortality. Clinical risk factors can identify patients most likely to have osteoporosis. Patients who have decreased bone mass are candidates for calcium and vitamin D supplementation; those who have more severe bone loss should be screened for secondary causes and started on medical therapy. First-line therapy most often is a bisphosphonate. Estrogen reduces hip fractures in women. Recombinant parathyroid hormone is reserved for patients who have failed or are not candidates for bisphosphonate therapy. Follow-up dual-emission x-ray absorptiometry is reserved for when a change in bone mineral density will make a difference in therapy.[Abstract] [Full Text] [Related] [New Search]