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  • Title: Fetal and umbilical flow velocity waveforms between 10-16 weeks' gestation: a preliminary study.
    Author: Wladimiroff JW, Huisman TW, Stewart PA.
    Journal: Obstet Gynecol; 1991 Nov; 78(5 Pt 1):812-4. PubMed ID: 1923203.
    Abstract:
    Maximal flow velocity waveform recording was attempted in the umbilical artery, fetal descending aorta, and at the fetal intracerebral level using a cross-sectional study design in 77 normal singleton pregnancies between 10-16 weeks' gestation. At 10-12 weeks, end-diastolic flow velocities were always absent in the fetal descending aorta and umbilical artery, but were present in 58% of the intracerebral artery waveforms. The pulsatility index at all three levels decreased significantly with advancing gestational age, suggesting a reduction in fetal and umbilical placental vascular resistance during the late first and early second trimesters of normal pregnancy. Waveform changes were not related to fetal heart rate.
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