These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Binding of 2-acetylaminofluorene-9-14C with rat liver nucleic acids during malignization and in primary hepatomas].
    Author: Ivanov SD, Dzhioev FK.
    Journal: Biull Eksp Biol Med; 1977 Mar; 83(3):332-4. PubMed ID: 192387.
    Abstract:
    The residual binding of 9-14C-2-Acetylaminofluorene (9-14C-2-AAF) with rat liver nuclei acids was investigated during hepatocarcinogenesis two weeks after a single injection of 9-14C-2-AAF. Up to 6 months feeding of the animals with unlabeled 2-AAF, the RNA of their liver proved to bind increased amounts of 9-14C-2-AAF in comparison with normal liver. The binding of 9-14C-2-AAF with DNA in primary hepatomas was mainly due to the RNA heterodispersed components with the maximum level in the 18S-fraction, as well as with the biopolymere fractions with the sedimentation constant of 10 and 5S enriched with polyadenylate fragments.
    [Abstract] [Full Text] [Related] [New Search]