These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Synthesis of aminocyclobutanes through ring expansion of N-vinyl-beta-lactams.
    Author: Cheung LL, Yudin AK.
    Journal: Org Lett; 2009 Mar 19; 11(6):1281-4. PubMed ID: 19239262.
    Abstract:
    Both eight-membered enamide rings and fused [4.2.0]aminocyclobutane-containing delta-lactams can be accessed from N-vinyl-beta-lactams. The eight-membered rings are made through a [3,3] sigmatropic rearrangement. At elevated temperature, the eight-membered lactam undergoes electrocyclization to furnish fused cyclobutane delta-lactams in a diastereoselective manner.
    [Abstract] [Full Text] [Related] [New Search]