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  • Title: Therapeutic ERCP and pregnancy: is the radiation risk for the conceptus trivial?
    Author: Samara ET, Stratakis J, Enele Melono JM, Mouzas IA, Perisinakis K, Damilakis J.
    Journal: Gastrointest Endosc; 2009 Apr; 69(4):824-31. PubMed ID: 19243762.
    Abstract:
    BACKGROUND: Symptomatic choledocholithiasis can be treated during pregnancy. Conceptus doses ranged from 0.1 mGy to 3 mGy in previous studies. OBJECTIVE: The objectives of the current study were to investigate whether the conceptus dose may exceed the threshold of 10 mGy in the case of a pregnant patient undergoing ERCP, and to provide data for the accurate assessment of a conceptus dose. DESIGN: Monte Carlo methodology and mathematical anthropomorphic phantoms were used to determine normalized conceptus dose data. Phantoms simulated pregnant patients of different body sizes and gestational stages. Monte Carlo simulations were performed to estimate the efficiency of external shielding. SETTING: University hospital. PATIENTS: Twenty-four consecutive patients. INTERVENTIONS: All patients underwent therapeutic ERCP. Exposure parameters and dose-area product were recorded during the procedures. MAIN OUTCOME MEASUREMENTS: The total dose-area product recorded during ERCP procedures ranged between 62 x 10(3) and 491 x 10(3) mGy . cm(2). RESULTS: Monte Carlo normalized conceptus dose data are presented as a function of kV(p), total filtration, gestational stage, and body mass index. The conceptus dose may exceed 10 mGy when the total dose-area product surpasses 130 mGy . cm(2). LIMITATIONS: Variations of conceptus location and size from the average. CONCLUSIONS: Conceptus dose from ERCP may occasionally exceed 10 mGy, the dose above which the analytical dose calculation is recommended. The use of external shielding is unnecessary because the associated dose reduction is negligible. The normalized dose data may be used for the accurate estimation of conceptus dose from an ERCP procedure performed on a pregnant patient, regardless of body size, gestational stage, operating parameters, and equipment used.
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