These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Combined indicators for diagnosing immune thrombocytopenic purpura].
    Author: Zhou J, Jiang NG, Kuang LH, Liao J.
    Journal: Sichuan Da Xue Xue Bao Yi Xue Ban; 2008 Nov; 39(6):1000-3. PubMed ID: 19253846.
    Abstract:
    OBJECTIVE: To search for the best combined indicators for diagnosing immune thrombocytopenic purpura (ITP). METHODS: Reticulated platelet (RP), thrombopoietin (TPO), platelet-associated immunoglobulins (PAIgG, by ELISA), mean platelet volume (MPV), platelet distribution width (PDW), platelet-large cell ratio(P-LCR) by flow cytometry), and automated blood cytometer were tested in three groups of people: patients with ITP (n=45), healthy people (n=45), and patients without ITP (n=42). Receiver operating characteristic (ROC) curve, LSD-t test, logistic regression, and correlation analysis were performed to identify the best indicators for diagnosing ITP. RESULTS: The patients with ITP had higher levels of RP, MPV, PDW, P-LCR, and PAIgG than the healthy people and the patients without ITP (P<0.05). The patients without ITP had higher TPO than the healthy people and the patients with ITP (P<0.05). RP and PAIgG were sensitive indicators to ITP. PR was correlated to the diagnosis of ITP (chi2=10.458, P=0.001). CONCLUSION: Individual indicator has limited diagnostic values for ITP, which could be improved by a combination of the indicators.
    [Abstract] [Full Text] [Related] [New Search]