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  • Title: [The electrocardiographic changes in patients with malignant neoplasms of the maxillofacial area during radio- and chemotherapy].
    Author: Kirsanov AI, Egorova LP, Kurlygina LA, Donchenko EV.
    Journal: Stomatologiia (Mosk); 1991; 70(3):40-3. PubMed ID: 1926207.
    Abstract:
    Electrocardiographic signs of changes in the myocardium were detected in 93.2 percent of 74 patients with malignant maxillofacial tumors; this was due to the presence of coronary disease, myocardial dystrophy, essential hypertension, respiratory abnormalities. The development and progress of these shifts much depended on radiotherapy and chemoradiotherapy of the tumors. The most frequent findings were deviations in the end section of the ventricular complex, reflecting the metabolic and ischemic changes in the myocardium, associated with a rise in radiation and polychemotherapy dosage. Extracoronarogenic myocardial lesions and coronary disease progression were clinically characterized by augmentation of cardiac insufficiency and various arrhythmias with mild pain syndrome. These specific clinical and electrocardiographic features of myocardial involvement should be borne in mind when choosing and carrying out radio- and polychemoradiotherapy of patients with maxillofacial tumors.
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