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  • Title: Two brothers with a symptomatic thoracic disc herniation at T11-T12: clinical report.
    Author: Overvliet GM, Beuls EA, Ter Laak-Poort M, Cornips EM.
    Journal: Acta Neurochir (Wien); 2009 Apr; 151(4):393-6. PubMed ID: 19266152.
    Abstract:
    BACKGROUND: In contrast to what is commonly believed, thoracic disc herniations are not rare lesions. Their etiopathogenesis is largely unknown, but may be linked to trauma, Scheuermann's disease or a degenerative back. OBJECTIVE: We report two brothers with a symptomatic thoracic disc herniation at T11-T12 and address the possibility of a genetic factor as well as other factors in the etiopathogenesis of (symptomatic) thoracic disc herniations. CLINICAL FEATURES: Both brothers were in their early thirties and had a physically demanding job, however, only the first one was a smoker and was diagnosed with Scheuermann's disease. CONCLUSION: The etiology of thoracic disc herniations is likely multifactorial. Their occurrence in siblings may reflect some genetic predisposition or may be merely coincidental, given the high prevalence of thoracic disc herniations in asymptomatic individuals. Further research, including genetic studies, is warranted.
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