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  • Title: [Medical therapy in peripheral arterial occlusive disease].
    Author: Périard D, Hayoz D, Mazzolai L.
    Journal: Rev Med Suisse; 2009 Feb 04; 5(189):312-5. PubMed ID: 19271648.
    Abstract:
    Atherosclerotic peripheral arterial disease (PAD) is often asymptomatic. If symptomatic, patients present intermittent claudication, ischemic rest pain or tissue necrosis. The prevalence of PAD increases with age and affects about 2% of patients at 60 years. Patients with PAD have an increased risk of coronary or cerebro-vascular events. Measure of the ankle-brachial index (ABI) allows early detection of asymptomatic patients, and allows early preventive interventions, in order to reduce their cardio-vascular risk. The most important interventions are smoking cessation, normalisation of blood pressure and lipid levels, and introduction of an antiplatelet agent, such as aspirin 75 to 160 mg/d.
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