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Title: [Macular and multifocal electroretinography in the diagnosis of Stargardt's dystrophy]. Author: Zol'nikova IV, Karlova IZ, Rogatina EV. Journal: Vestn Oftalmol; 2009; 125(1):41-6. PubMed ID: 19284101. Abstract: Retinal bioelectrical activity was studied in Stargardt's dystrophy from the data of multifocal and macular electroretinography (M-ERG) and retinal morphometry was carried out. The group of 11 patients (22 eyes) with the central form of Stargardt's dystrophy showed reductions in the retinal density of a bioelectric response of a P1 component, the amplitude of N1 and P1 components in the area of 0 to 16 degrees, as well as decreases in the amplitude of M-ERG a- and b-waves and in the retinal thickness in the macular region. The mixed Stargardt's dystrophy group was characterized by reductions in the retinal density of an electrical response of a P1 component, in the amplitude of N1 and P1 components in the entire posterior pole in the area of 0 to 32 degrees, as well as decreases in the a- and b-waves of M-ERG, photopic, scotopic, and mixed ERG; the lowered retinal thickness was found in the foveal and parafoveal regions. A statistically significant relationship was established between the morphometric indices of the volume of the central retina, the amplitude of M-ERG b-wave, and the moderate retinal density of P1 component bioelectrical activity in the central regions.[Abstract] [Full Text] [Related] [New Search]