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  • Title: [Disseminated tumor cell embolism of the lung as a cause of sudden death during general anesthesia].
    Author: Weidemann DM, de Jonge JP, Blessing MH, Doehn MH.
    Journal: Anaesthesist; 1991 Jul; 40(7):407-9. PubMed ID: 1928716.
    Abstract:
    A 56-year-old woman was hospitalized because of jaundice, vomiting, and weight loss. Diagnostic measures were almost all negative except for computer tomography of the abdomen, which revealed a cyst in the pancreas. During performance of a diagnostic laparotomy the patient suddenly died, presenting with cyanosis and untreatable circulatory failure with a markedly elevated central venous pressure. Autopsy revealed pulmonary tumor-cell embolization. This rare cause of sudden death is characterized by the discrepancy between the clinical picture and the virtually negative preoperative diagnostic results. We present this case report as a reminder of this clinical entity and recommend an autopsy in every case of unexpected death under anesthesia.
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