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  • Title: [Study on the slow release of silver ion from silver containing antibacterial HA coating material].
    Author: Zhu ZY, Zhang FQ, Zheng XB.
    Journal: Shanghai Kou Qiang Yi Xue; 2009 Feb; 18(1):66-8. PubMed ID: 19290431.
    Abstract:
    PURPOSE: To study the slow release of silver ion from silver containing antibacterial HA coating material. METHODS: Ti coated with HA samples were prepared using vacuum plasma spraying. In group 1, HA coating materials contained 5%(wt%) silver-zirconium phosphate antimicrobial. In Group 2, pure HA coating materials were used. The samples were immersed into the newborn calf serum and stored under anaerobic environment at constant temperatures of 37 degrees centigrade, avoiding light. The newborn calf serum was set as control. The Ag(+) ion concentration was detected and calculated using atomic absorption spectroscopy at 1,7,14 days. RESULTS: The Ag(+) ion contents of group 1 were 250 ng, 425 ng and 417 ng respectively at the end of 1,7,14 days. The release rate of Ag(+) ion became slow with the lapse of time. The release of Ag(+) ion became stable during 7-14 days. The Ag(+) ion content decreased on the 14th day. The Ag(+) ion content of group 2 could be ignored. CONCLUSIONS: The release of Ag(+) ion from silver containing HA coating materials is little and becomes stable on the 7th day. There might be reabsorption of Ag(+) ion on the 14th day.
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