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  • Title: 72 year-old man with new seizure while dancing.
    Author: Gutiérrez Morales JC, Gutiérrez Morales SE, Astudillo González A.
    Journal: Brain Pathol; 2009 Apr; 19(2):347-8. PubMed ID: 19291004.
    Abstract:
    Metastasis of an extracranial malignant neoplasm to a meningioma is a rare event.We report a case of a 72-year-old man who presented abruptly with a grand mal seizure. Neuroradiological examination revealed an extraaxial lesion located in the posterior right frontal convexity with poorly defined boundaries. Histological and immunohistochemical examination showed that the lesion was a meningothelial meningioma harboring metastatic renal cell carcinoma.The MRI could be indicative but not specific of this type of lesion.Some cases of intracranial meningiomas containing metastatic carcinomas have been published, but to our knowledge only five cases of renal cell carcinoma metastasizing to a meningioma have been reported. Possible explanations for this type of "tumor in tumor" lesion are reviewed.
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