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Title: Dramatic response of a gastrointestinal stromal tumor to neadjuvant imatinib therapy. Author: Annaberdyev S, Gibbons J, Hardacre JM. Journal: World J Surg Oncol; 2009 Mar 16; 7():30. PubMed ID: 19291285. Abstract: Gastrointestinal stromal tumors (GISTs) are the most common sarcoma of the alimentary tract and are believed to derive from the interstitial Cell of Cajal. Imatinib mesylate (Gleevec; Novartis, Basel, Switzerland) has revolutionized the treatment of GISTs and is generally used in the metastatic and adjuvant settings. We report the case of a 61-year old man who was treated with neoadjuvant imatinib for a massive gastric GIST with the hope of avoiding a potential multi-visceral resection.[Abstract] [Full Text] [Related] [New Search]