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  • Title: No sensory neuropathy during pyridoxine treatment in homocystinuria.
    Author: Mpofu C, Alani SM, Whitehouse C, Fowler B, Wraith JE.
    Journal: Arch Dis Child; 1991 Sep; 66(9):1081-2. PubMed ID: 1929522.
    Abstract:
    Seventeen patients with cystathionine synthase deficiency homocystinuria were examined clinically and neurophysiologically for evidence of sensory neuropathy. All had received high dose pyridoxine (vitamin B-6) for many years. Absence of neurological disturbance in all cases suggests long term treatment with pyridoxine in the dosages used in homocystinuric patients is not harmful.
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