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  • Title: Diabetes and hypertension: which is the best approach?
    Author: Escobar C, Barrios V.
    Journal: Expert Rev Cardiovasc Ther; 2009 Mar; 7(3):269-71. PubMed ID: 19296764.
    Abstract:
    Evaluation of: Ostergren J, Poulter NR, Sever PS et al. The Anglo-Scandinavian Cardiac Outcomes Trial: blood pressure-lowering limb: effects in patients with Type II diabetes. J. Hypertens. 26, 2103-2111 (2008). Although blood pressure control is crucial to improve cardiovascular prognosis in patients with diabetes and hypertension, less than 10% of these patients attain blood pressure goals. European guidelines recommend that combined therapy should be used as first-line treatment in this population. The next step in the treatment of these patients is to determine which combination is preferable for each situation. The results of the Anglo-Scandinavian Cardiac Outcomes Trial demonstrated the benefits of amlodipine-based treatment on the incidence of total cardiovascular events and procedures, compared with atenolol-based treatment. In this article the potential explanations of these results are discussed.
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