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  • Title: Stereoelectronic versus steric tuning in the prins cyclization reaction: synthesis of 2,6-trans pyranyl motifs.
    Author: Hu XH, Liu F, Loh TP.
    Journal: Org Lett; 2009 Apr 16; 11(8):1741-3. PubMed ID: 19301864.
    Abstract:
    The use of carboalkoxyl allenic alcohol for the efficient synthesis of pyranyl motifs via Prins cyclization is described. This method provides easy access to 2,6-trans dihydropyrans in good yield and high diastereoselectivity.
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