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  • Title: Robustness and topology of the yeast cell cycle Boolean network.
    Author: Lee WB, Huang JY.
    Journal: FEBS Lett; 2009 Mar 04; 583(5):927-32. PubMed ID: 19302794.
    Abstract:
    Yeast cell cycle Boolean network was used as a case study of robustness to protein noise. Robustness was interpreted as involving stability of G1 steady state and sequence of gene expression from cell cycle START to stationary G1. A robustness measure to evaluate robustness strength of a network was proposed. Robust putative networks corresponding to the same steady state and sequence of gene expression of wild-type network were sampled. Architecture of wild-type yeast cell cycle network can be revealed by average topology profile of sampled robust putative networks.
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