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  • Title: Protease responsive nanoprobes with tethered fluorogenic peptidyl 3-arylcoumarin substrates.
    Author: Welser K, Grilj J, Vauthey E, Aylott JW, Chan WC.
    Journal: Chem Commun (Camb); 2009 Feb 14; (6):671-3. PubMed ID: 19322417.
    Abstract:
    Protease responsive nanosensors were obtained by the attachment of unique green fluorescent bifunctional 3-arylcoumarin-derived fluorogenic substrates to poly(acrylamide-co-N-(3-aminopropyl)methacrylamide) nanoparticles, in which proteolysis results in substantial signal amplification.
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