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  • Title: [Anti-TNF alpha in the treatment of rheumatoid arthritis and ankylosing spondylitis].
    Author: Lanfant-Weybel K, Lequerré T, Vittecoq O.
    Journal: Presse Med; 2009 May; 38(5):774-87. PubMed ID: 19327945.
    Abstract:
    Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are, with psoriatic arthritis, the most frequent rheumatic diseases. A better understanding of pathophysiology of these diseases had led to the development of new treatments refered as to biologic agents and, among them, TNF blocking agents have a major role. The knowledge of these drugs in terms of mechanisms of action, indications and potentials side effects has to be known to improve the efficacy/tolerance balance. Although these 3 anti-TNFalpha agents are currently used, new TNF blocking agents are under evaluation and should increase the number of drugs available within the next months.
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