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  • Title: Cornoid lamellae associated with follicular infundibulum and acrosyringium in porokeratosis.
    Author: Minami-Hori M, Ishida-Yamamoto A, Iizuka H.
    Journal: J Dermatol; 2009 Mar; 36(3):125-30. PubMed ID: 19335685.
    Abstract:
    Skin lesions of porokeratosis consist of an atrophic center bordered by a peripheral grooved keratotic ridge that corresponds histopathologically to the cornoid lamella. Originally porokeratosis was named based on the assumption that the columns of parakeratosis emerge from the ostia of eccrine ducts. Despite this, it is generally accepted that the cornoid lamellae are rarely related to the acrosyringium. We recently encountered two cases of porokeratosis, where the cornoid lamellae were related to the follicular infundibulums. Therefore, we analyzed the location of the cornoid lamellae in 86 lesions of porokeratosis from 73 patients from our archives. We found that many cornoid lamellae are also detected at follicular infundibulum and acrosyringium. The existence of so many cornoid lamellae at follicular infundibulum and acrosyringium inside the plaques cannot be explained by pure coincidence and may be more than fortuitous.
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