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  • Title: Synthesis and antibacterial activities of novel oxazolidinones having spiro[2,4]heptane moieties.
    Author: Kim SY, Park HB, Cho JH, Yoo KH, Oh CH.
    Journal: Bioorg Med Chem Lett; 2009 May 01; 19(9):2558-61. PubMed ID: 19345578.
    Abstract:
    The synthesis of a new series of oxazolidinones having spiro[2,4]heptane moieties is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituents on the oxazolidinone ring was investigated. A particular compound Ih having fluoro group showed the most potent antibacterial activity.
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