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  • Title: Two novel monoterpene-chalcone conjugates isolated from the seeds of Alpinia katsumadai.
    Author: Hua SZ, Luo JG, Wang XB, Wang JS, Kong LY.
    Journal: Bioorg Med Chem Lett; 2009 May 15; 19(10):2728-30. PubMed ID: 19362829.
    Abstract:
    Three monoterpene-chalcone conjugates, including two novel compounds isorubraine (2) and sumadain C (3), and a known compound rubraine (1) were isolated from the seeds of Alpinia katsumadai. Their structures and relative configurations were established by NMR spectroscopy and X-ray crystallography. Cytotoxic activities of these compounds were evaluated against cell lines HepG2, MCF-7 and MAD-MB-435, and compound 3 exhibited potent cytotoxic activity.
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