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Title: Perioperative haemostatic management of Glanzmann thrombasthenia for abdominal surgery. Author: Lison S, Spannagl M, Heindl B. Journal: Blood Coagul Fibrinolysis; 2009 Jul; 20(5):371-3. PubMed ID: 19367156. Abstract: Glanzmann thrombasthenia is a rare congenital platelet disorder characterized by spontaneous mucocutaneous bleeding and severe bleeding complications during major surgery. This report centres on the perioperative haemostatic management of a patient with Glanzmann thrombasthenia undergoing elective major abdominal surgery. The treatment regimen was based mainly on recombinant activated factor VII, fibrinogen, and factor XIII, reducing platelet transfusion to a minimum. No red blood cell transfusions were needed perioperatively. For haemostatic monitoring, routine laboratory tests were sufficient.[Abstract] [Full Text] [Related] [New Search]