These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Peripapillary retinal nerve fiber layer thickness analysis with scanning laser polarimetry (GDx VCC) in normal children.
    Author: Salvetat ML, Zeppieri M, Felletti M, Parisi L, Brusini P.
    Journal: J Glaucoma; 2010 Jan; 19(1):51-7. PubMed ID: 19373102.
    Abstract:
    PURPOSE: To assess the use of scanning laser polarimeter with variable corneal compensation (GDx VCC) in children; to compare GDx VCC parameters between normal children and adults; and, to evaluate peripapillary retinal nerve fiber layer thickness variation with age in normals. PATIENTS AND METHODS: Ninety-eight normal children (mean age 8.5+/-2.8 y; range: 3 to 17) and 96 normal adults (mean age of 47.0+/-20.4 y; range: 18 to 87) underwent GDx VCC testing. Eyes with small or large optic discs were excluded. The "extended parameter table" parameters and mean thickness values of the 4 quadrants and 64 sectors were considered. Differences between age groups, retinal thickness comparisons and age effect were assessed using unpaired t test, analysis of variance, and regression analysis. RESULTS: GDx VCC parameters in children and adults showed wide intersubject variability. All parameters, excluding Symmetry, were significantly greater in children (P<0.05). TSNIT (temporal, superior, nasal, inferior, temporal) average, superior average and inferior average parameters showed a significant age-related thinning (P<0.01), at a rate of 0.043, 0.057, and 0.121 microm/y, respectively. CONCLUSIONS: A significant age-related superior and inferior retinal nerve fiber layer thinning was found using GDx VCC. Considering the significant differences between children and adults for most GDx VCC parameters, the built-in adult normative database cannot be applied in children.
    [Abstract] [Full Text] [Related] [New Search]